top of page

Publications

WVU

12.

Cowan, S.C., Ansari, A., Ross, M. R., Glenn, C.D., Hilton, M. J.  "Mechanistic Centrality of Boron-Containing Complexes in α-Hydroxy C–H Alkylation of Alcohols Promoted by Photoredox and Hydrogen Atom Transfer Catalysis.”

 

DOI: 10.26434/chemrxiv-2023-6ttgx

TOC.tif

Prior to WVU

11.

Hilton, M. J.; Brackett, C; Blagg, B.; Miller, S. J. “Catalysis-Enabled Access to Cryptic Geldanamycin Oxides”

 

ACS Cent Sci. 2020, 6, 426–435

TOC-2.jpg
10.

Coelho, J. A. S.; Matsumoto, A.; Orlandi, M.; Hilton, M. J.; Sigman, M. S. Toste, F. D. “Enantioselective fluorination of homoallylic alcohols enabled by the tuning of non-covalent interactions”

 

Chem. Sci. 2018, 9, 7153–7158.

TOC-chem sci 2018.jpg
9.

Orlandi, M.; Hilton, M. J.; Yamamoto, E.; Toste, F. D.; Sigman, M. S. "Mechanistic Investigations of the Pd(0)-Catalyzed Enantioselective 1,1-Diarylation of Benzyl Acrylates"

 

J. Am. Chem. Soc. 2017, 139, 12688.

toc-jacs 2017 - mech.jpg
8.

Orlandi, M.; Coelho, J. A. S.; Hilton, M. J.; Toste, F. D.; Sigman, M. S. “Parametrization of Non-covalent Interactions for Transition State Interrogation Applied to Asymmetric Catalysis”

 

J. Am. Chem. Soc. 2017, 139, 6803

toc-jacs 2017 param.jpg
7.

Neel, A.; Hilton, M. J.; Sigman, M. S.; Toste, F. D. “Exploiting Noncovalent π Interactions for Catalyst Design”

 

Nature 2017, 543, 637.

TOC Nature 2017.tif
6.

Hilton, M. J.; Sigman, M. S.* "(S)-4-(tert-Butyl)-2-[4-(trifluoromethyl) pyridin-2-yl]-4,5-dihydrooxazole"

 

Encyclopedia of Reagents for Organic Synthesis; John Wiley & Sons, Ltd: 2016.

TOC-pyrox.tif
5.

Yamamoto, E.*; Hilton, M. J.*; Orlandi, M.; Saini, V.; Toste, F. D; Sigman, M. S. “Development and Analysis of a Pd(0)-Catalyzed Enantioselective 1,1-Diarylation of Acrylates Enabled by Chiral Anion Phase-Transfer” *contributed equally

 

J. Am. Chem. Soc. 2016, 138, 15877. 

TOC.tif
4.

Chen, Z.-M.; Hilton, M. J.; Sigman, M. S. “Palladium-Catalyzed Enantioselective Redox-Relay Heck Arylation of 1,1-Disubstituted Homoallylic Alcohols”

 

J. Am. Chem. Soc. 2016, 138, 11461‒11464.

TOC.tif
3.

Invited article for a special issue, honoring Jiro Tsuji:

      Hilton, M. J.; Cheng, B.; Buckley, B. R.; Xu, L.; Wiest, O.; Sigman, M. S.* “Relative reactivity of alkenyl alcohols in the palladium-catalyzed redox-relay Heck reaction”

 

Tetrahedron 2015, 71, 6513–6518.

 

​

TOC-tetrahedron.jpg
2.

Featured article for the special issue “Mechanisms in Metal-Based Organic Chemistry”

      Hilton, M. J.; Xu, L.-P.; Norrby, P.-O.; Wu, Y.-D.; Wiest, O.; Sigman, M. S. “Investigating the Nature of Palladium Chain-Walking in the Enantioselective Redox-Relay Heck Reaction of Alkenyl Alcohols" 

 

J. Org. Chem. 2014, 79, 11841‒11850.

TOC deuterium.jpg
1.

Xu, L.; Hilton, M. J.; Zhang, X.; Norrby, P.-O.; Wu, Y.-D.; Sigman, M.S.; Wiest, O. "Mechanism, Reactivity and Selectivity in Palladium-Catalyzed Redox-Relay Heck Arylations of Alkenyl Alcohols"

 

J. Am. Chem. Soc. 2014, 136, 1960‒1967.

TOC- jacs 2014.jpg
bottom of page